Predicting the Impact of cis-Regulatory Variation on Alternative Polyadenylation
Journal: Bogard N, Linder J, Rosenberg AB, Seelig G , (). Predicting the Impact of cis-Regulatory Variation on Alternative Polyadenylation bioRxiv . ,
Abstract:Alternative polyadenylation (APA) is a major driver of transcriptome diversity in human cells. Here, we use deep learning to predict APA from DNA sequence alone. We trained our model (APARENT, APA REgression NeT) on isoform expression data from over three million …
URL: https://www.biorxiv.org/content/early/2018/04/12/300061.abstract
