Multiplexed Exchange-PAINT imaging reveals ligand-dependent EGFR and Met interactions in the plasma membrane
Journal: Werbin JL, Avendaño MS, Becker V, Jungmann R, et al. , (). Multiplexed Exchange-PAINT imaging reveals ligand-dependent EGFR and Met interactions in the plasma membrane Sci. Rep. . ,
Abstract:Signal transduction by receptor tyrosine kinases (RTKs) involves complex ligand-and time- dependent changes in conformation and modification state. High resolution structures are available for individual receptors dimers, but less is known about receptor clusters that form …