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Multiplexed Exchange-PAINT imaging reveals ligand-dependent EGFR and Met interactions in the plasma membrane


Journal:
Werbin JL, Avendaño MS, Becker V, Jungmann R, et al. , (). Multiplexed Exchange-PAINT imaging reveals ligand-dependent EGFR and Met interactions in the plasma membrane Sci. Rep. . ,

Abstract:

Signal transduction by receptor tyrosine kinases (RTKs) involves complex ligand-and time- dependent changes in conformation and modification state. High resolution structures are available for individual receptors dimers, but less is known about receptor clusters that form …

URL: https://www.nature.com/articles/s41598-017-12257-y

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