Single-molecule RNA detection at depth via hybridization chain reaction and tissue hydrogel embedding and clearing
Journal: Shah S, Lubeck E, Schwarzkopf M, He TF, et al. , (). Single-molecule RNA detection at depth via hybridization chain reaction and tissue hydrogel embedding and clearing . ,
Abstract:Accurate and robust detection of mRNA molecules in thick tissue samples can reveal gene expression patterns in single cells within their native environment. Preserving spatial relationships while accessing the transcriptome of selected cells is a crucial feature for …
URL: http://dev.biologists.org/content/early/2016/06/23/dev.138560.abstract
